I thought this was a particularly poignant picture from Earl Dotter's book:
Mr. Dotter first encountered what was to become the inspiration for this book's title in a humble textile mill community in Greenville, South Carolina. As it turned out, the village's cotton mill workers had contracted Brown Lung disease as a consequence of exposure to cotton dust while on the job at the local mill. Byssinosis victims cannot usually sleep through the night due to constant coughing brought on by the disease. The community had these signs erected to help victims rest at any time of day.
Scroll down here, and you can survey other pictures from his book from different categories.